Real tools, real trade-offs
Medications
Prescription medicine with real mechanisms and real evidence — and real side effects, costs, and unknowns. We give the adult version: what it does, what the trials actually show, and where it belongs. All of it is a conversation with a clinician, not a self-serve decision.
11 entries · roughly 3% of what moves the needle
Medications
Statins
The most-studied cardiovascular drug there is — strong, cheap, and considerably better tolerated than its reputation suggests.
Medications
GLP-1 (semaglutide)
A genuinely powerful class of medication for obesity and cardiometabolic risk — with strong trial evidence, real side effects, and a cost profile that belongs in a medical decision.
Medications
SGLT2 inhibitors
Diabetes drugs that turned out to protect the heart and kidneys, now used well beyond glucose control.
Medications
PCSK9 inhibitors
Injectable antibodies that drive LDL to strikingly low levels, with proven cardiovascular event reduction for high-risk patients — held back mainly by cost and access.
Medications
Ezetimibe
A well-tolerated pill that lowers LDL by blocking its absorption in the gut, with proven incremental event reduction when added on top of a statin.
Medications
Metformin
The first-line drug for type 2 diabetes with a strong, decades-deep safety record — and an anti-aging reputation that has gotten well ahead of what's actually been shown in humans.
Medications
Tadalafil
A long-acting PDE5 inhibitor taken as a low daily dose — FDA-approved for both erectile dysfunction and benign prostatic hyperplasia, cheap as a generic, and generally well tolerated.
Medications
Testosterone (TRT)
Appropriate treatment for diagnosed hypogonadism — not an anti-aging shortcut for normal men.
Medications
Low-dose aspirin
Valuable after a cardiovascular event, but for primary prevention the bleeding risk usually outweighs the benefit.
Medications
Enclomiphene
A SERM that raises the body's own testosterone by nudging LH and FSH — preserving fertility unlike TRT — but not FDA-approved and available only through compounding.
Medications
LDN
Naltrexone at a fraction of its usual dose (1.5–4.5 mg), used off-label for chronic pain, fibromyalgia, and some autoimmune conditions on genuinely thin but interesting evidence.